PHARMACEUTICS
I 1) Pharmaceutical technology
2) Formulative & Industrial pharmacy
3) Physical Pharmacy
4) Hospital & clinical pharmacy
5) Bio Pharmaceutics
II Bio Technology
III Forensic Pharmacy
Pharmacy Act 1948
Drugs & Cosmetics Act 1940
Narcotic & Psychotropic Substances Act.
PHARMACY - I
Pharmacology
Pharmacognosy
Pharmaceutical Chemistry
a) Chemistry of Natural Products
b) Medicinal Chemistry
c) Modern method of pharmaceutical analysis
PHARMACY - II
PHARMACEUTICS:
I Pharmaceutical Technology:-
(i) The Physical Physico-Chemical and Engineering Principles
governing design, lay-out and operation of plants for
the process employed in Pharmaceutical Industry - Size
Reduction, Size seperation, mixing, compression, filtration,
centrifugation, Extraction, Evaporation, Drying, Distillation,
Crystallization.
(ii) Safety methods of Pharmaceutical laboratories and
work.
(iii) containers and closures and packaging technology.
II Hospital and Clinical Pharmacy:- (a)
(i) Hospital Pharmacy - its aims, organisation, personnel
and functions.
(ii) Drug Distribution system in Hospital.
(iii) Drug information centre
(iv) Purchasing, inventory control and pricing of drugs.
III (b) (i) Clinical Pharmacy - its concept and functions.
(ii) Design and optimization of dosage regimen
(iii) Therapeutic drug mointoring
(iv) Adverse drug reactions.
IV Formulative and
Industrial Pharmacy:-
(I) Preformulation Studies:-
Dosage form Necessities:-
Antioxidant, Preservatives, Colouring, Flavouring and
Sweetenning agents, Solvents Facts related with formulation,
Physical properties, particle size, crystal form, flow
cohesiveness, solubility, Chemical properties, hydrolysis,
oxidation, racenization enzymatic decompositions.
V Technology of Drug
Delivery Systems:-
Good Manufacturing Practice, Standards, Presents labelling
packing, and storage, quality assurance and quality
control of formulation belonging to the following categories.
Semisolid Preparations:- Ointments, Pastes, Creams,
gels Jellies and Suppositories.
Solid dosage forms:- Powders, Tablets, Capsules
Liquid dosage forms:- Mixtures, Elixirs, Syrups, Collodions
throatpaints, and enemas, official in various pharmacopoeias.
Parentral and opthalmic Preparations:- Injections, Sterile
powders, Depots, Implants, eye drops and eye ointments.
New Drug Delivery Systems:- Aerosols, Occusert, Transdermal
Drug delivery, Osmotic drug delivery, Targetted drug
delivery systems, Radio Pharmaceuticals.
Cosmetics:- Dentrifrices, Lipstick, face powders, shampoos,
deplitatories and manicure preparations.
VI Community Pharmacy:-
Dispensing and compounding Procedures and containers
and closures for packaging, with regard to-Mixtures,
emlusions, applications, inhalations, spray solutions,
powders, powders in hard gelatin capsules, tablet triturates,
mouthwash, gargles, eyelotion, douches.
VII Application of
computer in pharmacy:-
Physical Pharmaceutics:- Principles related with Rheology,
surface and interfacial phenomenon, Soulbilization,
Thermodynamics, Complexation and protein binding.
VIII Bio Pharmaceutics:-
Basic of Pharmacodynamic and pharmacekinetic and their
importance in formulation.
IX Pharmaceutical
Bio - Technology:- (i) Bio - Chemical role of hermenes,
vitamines, enzymes and nuclic acids.
(ii) Principles involved and apparatus used in the analysis
of blood, urine, gastric, juices, faeces etc.
(iii) General principles of immunology, Immunology techniques
used in pharmacy.
(iv) Sterilization of different pharmaceutical desage
forms.
(v) Steribility testing
(vi) Methods of Preparation of official Sera and Vaccines.
(vii) Microbiological assays of the pharmacopoeia
(viii) Applications of Micro - organisms in bio-conversions
and pharmaceutical industry.
X Forensic Pharmacy:-
(i) Pharmacy act 1948
(ii) Drugs and cosmetics Act - 1940 - Rules 1945
(iii) Narcotic and Psychotropic drugs act 1986.
PAPER -II
PHARMACOLOGY
1. General Pharmacology:- Routes of administration -
Absorption, distribution, Biotransformation & Extretion
of drugs. - Bioavailability and bio equivalence - Factors
affecting bioavaliability. - Mechanism of action of
drugs at receptor level - adverse drug reaction
2. Drugs acting on Central Nervous system:- - Analgesics
- Nensterodial anti inflammatory drugs - Sedatives and
Hypnotics - Anti convulsants and Antipsychotic drugs.
- Central Nervous System stimulants, which are in frequent
use (or) which are of toxicological importance.
3. Drugs acting on Autonomic Nervous system:- - Drugs
which influence the working of autonomic nervous system
- Adrenergic drugs (or) sympathominitic drugs - Adrenergic
blocking drugs. - Cholinergic drugs and cholinergic
blocking drugs. - Drugs acting on autonomic ganglia
- Drugs used in parkinsonism and Myasthenia gravis
4. Drug acting on Gardiovasular system cardiac glycosides,
Anti typertensive, anti array thmic, and anti anginal
drugs.
5. Diuretics of anti diuretics.
6. Insulin and oral anti diabetic drugs, Thyroid and
antithroidal drugs, oral contraceptives, Hormone replacement
thereapy, family planning methods.
7. Study of Antihistaminics, and drugs acting on uterus.
8. Chemotherapy of infections diseases sulphonamides,
penicillins, - antibiotics Chemotheraphy of Tuberculosis
- leprosy malaria, cancer Ameebiasis, Helminthisis and
veneral diseases.
9. Toxicology:- Systematic & local treatment of
poisoning and their treatment.
10. Principles of biological assay, classification,
with examples from therapeutics and also listed in I.P.
PHARMACOGNOSY
1. General principle of cultivation and collection of
drugs from wild & cultivated sources, their merits
and demerits factors affecting. Plant growth regulators,
Basics of genetic engineering, drug detnoration - causative
factors prevention. Adulteration and its detection.
2. Pharmacognositc scheme work of (source, synomym,
Cultivation. Collection, Preparation for market, diagnostic
charactors (both macroscopical and microscopical), constituents,
substitutents, adulterants and uses of) Cinnamon, Cinchona,
Seena, Digitalis, Clove, saffron Pyrethrum, cochineal,
Ergot, opium, Aloe, Acacla, Tragacanth, Benzoin, Ginseng,
Brahmi, Diosoorea, Cascara, Gelatin umbelliforous fruits.
3. Basic concept involved in Ayurveda, Siddha, Unani,
Naturopathy.
4. Principle and Application of plant tissue culture
5. Basics of fermentation technology & production
of Antibiotics, Vitamins.
6. Principle & Application of Tracer technique.
7. Biosythetic pathways of Tropane alkaloids, cholesterol,
amino acids.
8. Definition, classification with structures, physical,
chemical properties and functions, of Alkaloids, Glycosides,
Resins, Tannins, Terpenes, Carbohydrates, Volatile oils,
fixed oils, with Examples.
9. Drug evaluation.
10. Phytochemical - Investigation of drugs (Screening
methods) including modern analytical techniques.
PHARMACEUTICAL
CHEMISTRY
a) Chemistry of Natural Products:- Familiarity with
methods of structure elucidation and biosythesis of
Alkaloids, Terpenrs, Steroids, Carbohydrates, Proteins.
Methods of extraction, classification, Chemistry Assay
and Medicinal uses of polysaccharides, amino acids,
pepticles, Glycosides, Vitamins and Hormones.
b) Miedicinal Chemistry:- Definition, classification,
sythesis, properties, test for purity, common names
structure, storage of drugs possessing the Following
pharmacological action. Analgesics and Antipyretics,
Antihistamines, Hypnotics and sedatives, antimalarials,
antibiotic, antihypertensives, sulphonamideo Anti psychotic
drugs, cardiac drugs diusetics.
c) Pharmaceutical Analysis:- Assay procedure of advances
types from the I.P. with special reference to the procedure
and techniques involving Non-Aqucous titrations, oxidation
- reduction, diazotization and complexometric methods
and grammetric analysis.
Chromatography
a) This layer chromatography
b) Column "
c) Paper "
d) Gas "
e) Ion exchange "
f) Gel electro phorosis
Theory, principle instruments involved and application
of colosimetry UV and visible spectrometry, Fluorimetry,
Nephalemetry, Tuebisimetry, potentiometric titration,
conductometric, titration, polarography, amperometric
titration. Basic of I.R. MASS, NMR
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