Related Links
   HOME
 

 



 
POST GRADUATE DEGREE STANDARD

PAPER - I CODE:047

 

Paper I (Section-A )

1. Molecular Pharmacology
i Drug Receptors
ii Chemical Bonds
iii Drugs And Enzymes
iv Structure Activity Relationship

2. Cellular Pharmacology
i Biological Membrane And Transport Accross Membranes
ii Drug Effect On Extra Cellular. Tissue Ingredients.

3. Integral Pharmacology
i Pharmacokinetics
ii Principal Effects Of Drugs
iii Side Effects Of Drugs
iv Complex Drug Actions - Commulation, Tolerence, Synergism, Antagonism, Potentiation.

4. Pharmacogenetics
5. Drug Selectivity
6. Chemotheraphy
i General Principles Of Chemotheropy
ii Chemotherapy Of Infectious Diseases
iii Chemotherapy Of Malignancy

7. Quantative Aspects In Pharmacology
i Dose Response Relationship
ii Bioassay
iii Chemical Assay
iv Radio Immuno Assay
v Drug Standardization

8. Pharmacological Screening Of Siddha
Medicinal Preparations
i Selection Of Plants, Minerals And Animal Products
Used In Siddha Medicine

ii Extraction,Preparation And Screening Of
Pharmacologically Active Principles In Various
Experimental Models.


9.Biostatistics
CenteringConstants;Means,MedianAndMode,Variability Constants- Average,Range,Interquartile Range, Average Deviation,
Standard Deviation;
Tests Of Significance Student'sTest, Chi Square Test, Anova, Application Of Statistics In Evaluation Of Siddha And Herbal Preparations And Formulations


Paper I (Section - B)

General Principles Of Toxicology

1 Introduction To Toxicology- Toxicology - Definition And Branches - Classification Of Toxic Agents.

2 Toxins - Acute And Chronic Exposure - Route, Site, Duration And Frequency Of Exposure.

3 Spectrum Of Toxic Effects - Allergic And Idiosyncratic Reactions; Toxicity; Immediate And Delayed; Reversible And Irreversible; Local Systemic And Selective.

4 Toxicokinetics - Abserption, Distribution, Metabolism And Excretion And Influencing Factors.

5 Dose - Response Relationship - Ld 50, Ed 50

6 Mechanism Of Action.

7 Chemical - Chemical Interaction, Chemical - Diet Interation - Potentiation, Synergism And Antagonism.

8 Factors Influencing Toxicity - Factors Related To The Agent, Exposure Situation And Internal Environment Of The Subject, External Enviornmental Factors.

9 ToxicityTestsInAnimals-Acute,Subacute And ChronicTests Mutagenicity,Teratogenicity And 0.Carcinogenicity
Tests, Interpretation Of Laboratory Data.

10 Treatment And Management Of Poisoning - Antidotal Principles And Their Application.

Paper I (Section-C)

Instrumentation

1 Thin Layer Chromatography & Paper Electrophoresis
2 U.V. - Vis Spectro Photometry - Differential Spectrophotometry
3 Infra-Red Spectrophotometry - Interpretation Of Spectra.
4 NMR Spectorphotometry And Its Applications.
5 Mass Spectrometry As Applied To Drugs Analysis
6 Gaschromatography & G C - Ms Techniques.
7 Atomic Absorption Spectrophotometry And Neutron Activation
Analysis As Applied To Elemental Analysis.
8 X-Ray Diffraction In Toxicological Analysis
9 High Performance Liquid Chromatography In Toxicology
10 Radio Immuno Assay In Analysis Of Body Fluids For Poisons.

PAPER -II



Paper II (Section-A)

I. Drugs Acting On Various Systems


i Cns
ii Ans
iii Respiratory
iv Cardio Vasular
v Gastrointestinal
vi Genito Urinary
vii Musculo Skeletal

II. Reproductive Pharmacology : -

(i) Drugs Acting On The Male & Female Reproductive System
(ii) Antifertility Agents
(iii) Hormone Replacement Therapy

III. Hormones And Hormone Antagonists : -

(i) Endocrinological Disorders And Drug Treatment
(ii) Anti Diabetic Drugs
(iii) Anti Thyroid Drugs
(iv) Hormone Replacement Therapy in Endocrinological Disorders

IV. Vitamins, Minerals And Nutritional Supplements:-

(i) Deficiencies And their Drug Treatment.

V. Analgesic, Anti Pyretic And Antinflammartory Drugs -

Drugs Used In Inflammatory Disorders - Anti Artheritic, Gout Drugs.

VI. Chemotherapy

General Principles - Chemotherapy Of Infectious Diseases, Chemotherapy Of Malignancy.

Paper II (Section-B )

1. Preliminaries - Central & Peripherac Nervous Systems Neuro Transmitters
2. Drug Addiction & Habituation
3. Drug Dependence
4. Social & Personality Factors Conductive To Drug Dependence
5. Dependence Potential And Dependence Liability
6. Narcotic Analgesies
7. Cannabis And Cannabenoids
8. Psychotogenic Drugs.
9. Amphetamines.
10. Cocaine And Erythroxylon Coca
11. Mono Amine Oxidase Inhibitors - Triexelic Antidepressants
12. Xanthine Beverages And Xanthine Alkaloids
13. Abuse Of & Toxicity Associated With Hypnotics And Seditives.

(i) Barbiturates
(ii) Benzodiazepines
(iii) Miscellaneous

14. (i) Acute & Chronic Toxicity Associated With Abeottol Abuse
(ii) Toxicity & Treatment Associated With Methanol Poisioning

15. Abuse Of Inhalants & Glue Sniffing.
16. Tobacco Smoking - Tobacco Use - Toxicity & Complications Associated With
17. Treatment & Prevention Of Drug Addiction.
18. Siddha & Other Methods Associated With The Treatment & Prevention Of Drug Addiction
19. Siddha Drugs In Preventing & Treating Drug Toxicity Associated With Liver And Other Organs.
20. Experimental Techniques In Evaluating The Addiction Potential And Liability Of A Drug.

Paper II (Section-C)

Forensic Toxicology

1 Poisons Acts And Type Of Poisoning In India.
2 Mode Of Action of Poisons.
3 Causes Which Modify The Effects
4 Corrosive Poisons
5 Metals And Their Salts And Methods Of Estimation
6 Volatile Poisons - Mode Of Action And Analysis
7 Insecticides
8 Synthetic Drugs
9 Plant Poisons And Animal Poisons-Isolation From Body Fluids.
10 Extraction And Purification In Toxicological Analysis.
11 Screening Tests For Common Poisons.
12 Gas Analysis.
13 Glycosides And Alkaloids And Analysis From Biological Fluids
14 Barbiturates And Other Synthetic Drugs
15 Metabolic Pathways Of Poisons

 
 
Copyright © 2005 TNPSC. All rights reserved.