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GRADUATE DEGREE STANDARD |
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PAPER
- I
BASIC SCIENCES
UNIT I
MICROBIOLOGY:
(a) Microbiology classification, monophology, characterisation
and isolation
(b) Metabolism, Growth
(c) Environmental effect
(d) Axenic mixed culture concept - interaction and ecosystem
model.
UNIT
II
IMMUNOLOGY AND VIROLOGY:
(a) Immunity and antibodies,
(b) Immuno regulations
(c) Molecular variability of antibody specificity
(d) Immunological techniques - immuno electrophoresis
- etc.,
(e) Ultrastructure of viruses,
(f) DNA and RNA viruses
(g) Viral infections
(h) Retroviruses
(i) Interferons - mechanism of action ect.,
UNIT
III
CELL AND TISSUE CULTURE:
(a) Different cell lines - characterisation and maintenance
(b) Hybridoma technology
(c) Tissue organisation
(d) Mechanical factors analysis.
UNIT
IV
GENETICS AND MOLECULAR BIOLOGY:
(a) Chromosome, Plasmids
(b) Genetic mapping
(c) Mandelian and Non-Mandelian Principles
(d) Genetics and Society
(e) DNA and RNA
(f) Coding system - genetic regulation
(g) Operon - promoter - repressor relation
(h) Eucaryotic regulation
UNIT
V
APPLIED GENETICS
(a) R-DNA Protoplast Fusion
(b) Role of d NTPs
(c) In vitro DNA Synthesis
(d) Site - directed mutagenesis - PCR, SSDNA and DSDNA
Cloning
(f) Vectors - Properties etc., Restriction mapping
(g) c DNA and Genomic library
(h) RFLP
UNIT
VI
PHYSIOLOGY
(a) Special Sensery mechanisms
(b) Body fluids - Properties etc.,
(c) Histological studies of organs and tissues
UNIT
VII
BIOCHEMISTRY AND BIOPHYSICS:
(a) Supra molecular assemblies
(b) Biomembrane
(c) Metabolism
(d) Bioenergetis
(e) Biopolymer structure and function
(f) Irreversible thermodynamics in biology
UNIT
VIII
BIO-INORGANIC & BIO-ORGANIC CHEMISTRY :
(a) Metalloproteins
(b) Transition metal in biological reactions
(c) Role of chelating agents and metals in medicine
(d) Trace elements absorbtion
(e) Transport and tissue storage
(f) Carbohydrate biopolymers
(g) Glycoproteins
UNIT
IX
MEMBRANE SCIENCE
(a) Analysis of membrane assymetry
(b) Lipid - protein interactions
(c) Lipid components in membranes
(d) Lipsomes
(e) Membrane potentials
(f) Membrane bound enzymes, transport and receptors
UNIT
X
BIO ANALYTICAL TECHNIQUES
(a) IR, NMR, Mass spectrometry principles
(b) Ion beam technique
(c) Time resolved fluorescenes spectroscopy
(d) X-ray crystallography
(e) Microscopy
(f) Spectrometry, fluorimetry etc.,
PAPER - II
APPLIED & ENGINEERING SUBJECTS
UNIT
I
BIO-PROCESS TECHNOLOGY:- (a) Energy, Mass and momentum
transfer
(b) Material and enrgy balances
(c) Upstreaming operations - Sterilization, air filter
design
(d) Biological process principle
(e) Statistical optimisation techniques in biological
system - Plackett - Burman, CCD, ANOVA analysis and
contour interpretation.
(f) Cellualar and enzymatic reactions.
UNIT
II
PROTEIN ENGINEERING AND BIO-INFORMATICS:-
(a) Protein data bank
(b) Protein structures; structure & function analysis
(c) Domain analysis in proteins
(d) Protein design, protein sequencing
UNIT
III
BIO-CONVERSION AND FERMENTATION TECHNOLOGY:-
(a) Bioconversion of starch, cellulose, corn
(b) Bioenrgy production
(c) Industrial applications of cells and enzymes
(d) Biopolymer design and synthesis
(e) Fermentation technologies for waste stabilization
and bio-product synthesis.
(f) Antibiotics and steroid fermentation
UNIT
IV
DOWNSTREAM TECHNOLGY:-
(a) Flocculation, Coagulation, Centrifugation
(b) Equiilibrium (statge) processes - distillation and
liquid - liquid extraction.
(c) Chromatography - GPC, Ion-exchange, affinity
(d) Separation of intracellular products
(e) Membrane Separations - Reverse Osmosis, ultrafiltration,
Microfiltration
(f) Aqueous two phase system
(g) Supercritical fluid extraction.
UNIT
V
KINETICS AND THERMODYNAMICS IN BIO-PROCESSES:-
(a) Moinod's equation - generalized Monod' equaiton
(b) Structured models
(c) Application of Arrhenius equation
(d) Stability analysis of cellular and enzymati porcesses
- D*, DS*, DH* calculation.
UNIT
VI
BIO-REACTORS:-
(a) Basic principles of bioreactors
(b) Configuration and their analysis
(c) Non-ideal effects
(d) Control of bioreactor
(e) Bioreactor modelling and stability analysis
(f) Mechanical design concept
UNIT
VII
PROCESS DESIGN AND SCALE-UP:-
(a) Flow sheet analysis
(b) Identification of crucial factors in processes
(c) Computer - aided design
(d) Scale-up criteria - k,a, power number etc.,
(e) Economic analysis for process scale-up and scale-down
UNIT
VIII
FOOD TECHNOLOGY:-
(a) Components in food
(b) Basal metabolic rate
(c) Long term preservation - canning, freeze drying,
sprary drying
(d) UHT concept and pasteurization
UNIT
IX
PHARMACEUTICAL SCIENCE AND ENGINEERING:-
(a) Pharmacekinetics
(b) Major unit operations in pharmaceutical processing
of antibiotics., life saving drugs and their formulation.
(c) Concept of LD50.
UNIT
X
LABORATORY HYGIENE AND ENVIRONMENT SAFETY:-
(a) Biosafety regulations
(b) Handling of genetically enginured organisms
(c) Disposal of radioactive components and otehr health
hazard substances
(d) Public health and pollution problems
(e) Waste management, recycling
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