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GRADUATE DEGREE STANDARD |
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PAPER-I
UNIT I
GENERAL PRINCIPLES OF PHARMACOLOGY:- 1. History of Pharmacology
and its evolution.
2. General Introductory pharmacology - Principles of
Pharmacokinetics (PCK) Principles of Pharmacodynamics
(PD) Drug theropy principles in geriatric and pediatric
patients. Principles of drug therapy in pregnancy and
lactation.
3. General principles of Pharmacogenctics - Heritable
factors influencing drugs Alterations in genetic system
by drugs.
4. Fetal Therapy.
UNIT
II
SYSTEMIC PHARMACOLOGY:- 1. Effect of drugs on Cardiovascular
system Central and Autonomic nervous system Gastro intestinal
system, Genito urinary system Musculo-skeletal system
Hematopoietic system
2. Drugs influencing immune responses - immunomodulators.
3. Pharmacology of autocoids & temperature regulating
systems.
4. Miscellaneous - Vitamines, Hormones as drugs, Heavy
metals and Chelating agents.
UNIT
III
CLINICAL PHARMACOLOGY:- 1. Drug safety and efficacy
2. Primary screening and conduct of drug trials. preclinical
trials, Phase I,II, III and IV trials.
3. Monitoring of adverse drug reactions and drug interactions.
4. Drug monitoring -Therapcutic drug monitoring.
5. Rational prescribing and pharmacocconomics.
UNIT
IV
EVALUATION OF DRUGS AND EXPERIMENTAL METHODS - BOTH
QUALITATIVE AND QUANTITATIVE ASPECTS:-
1. Elucidation/Evaluation of mechanism of drug action
on various systems lic - CNS, CVS, GIT, GUT, endocrine,
Respiratory, Immune function, diuresis etc.,
2. Methods in acute and chromic toxis studies.
3. Methods in phytochemistry.
UNIT
V
RECENT ADVANCES IN PHARMACOLOGY:-
PAPER-II
UNIT
I
GENERAL PRINCIPLES OF PHARMACOLOGY:- 1. General Principles
of Toxicology of Xcnobiotics, Environmental pollutants
and Pharmacocpidemiology.
2. General Principles of Clinical Pharmacology.
3. Principles of Bioassy and Drug monitoring.
UNIT
II
SYSTEMIC PHARMACOLOGY:-
1. Toxicology - Treatment of poisoning /overdose.
2. Social Pharmacology & Pharmacoeconomic
UNIT
III
APPLIED PHARMACOLOGY:- 1. Pharmacology of Infectious
diseases (parasitic, fungal, bacterial, viral etc.,)
2. Therapy of disease due to chemical, physical, climatic
& environmental causes.
3. Therapy of dis.due to genetic & constitutional
factors.
4. Drug therapy in the young and neonate, old patients.
5. Drug therapy of neuropsychiatrid syndromes.
6. Basic knowledge of anatomy, physiology, biochemistry,
Microbiology and pathology, cellular and molecular biology
applied to pharmacology.
UNIT
IV
EVALUATION OF DRUGS AND EXPERIMENTAL METHODS - BOTH
QUALITATIVE AND QUANTITATIVE ASPECTS:- 1. Biological
standardisations - ID50 ED50 etc., in intact and isolated
preparations.
2. Methods of pharmacokinctics - measurements of PL.
conc. Elim t 1/2 vd, AUC, pcak pl conc vs. through conc
etc.,
3. Basic principles of instrumentation PH meter spectrophotometer
(UV-Vis & flourescence), Flamcphotometry, Chromatography,
HPIC, Electrophores is and use of computers in pharmacology.
UNIT
V
PROGRESS IN MEDICINAL CHEMISTRYCURRENT TRENDS:-
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